Charles Leduc

Pathologie des maladies pulmonaires, cardiovasculaires, et médiastinales.
Professeur agrégé de clinique
Faculté de médecine - Département de pathologie et biologie cellulaire
514 890-8000, poste 20978
514 412-7396 (Télécopieur)

Expertise de recherche


  • Pathologie pulmonaire
  • Pathologie médiastinale
  • Pathologie cardiovasculaire



  • Fellowship en pathologie cardiovasculaire (Mayo Clinic, USA)
  • Fellowship en pathologie thoracique (Memorial Sloan Kettering Cancer Center, USA)
  • Diplôme en médecine (Université McGill, Québec)
  • Maîtrise en sciences (Département de pharmacologie, Université de Montréal, Québec)


  • Chaix M, Chergui M, Leduc C, Khairy P. Histopathological evidence of acute myocardial ischemia as the cause of sudden death in transposition of the great arteries with atrial switch despite normal coronary arteries. International Journal of Cardiology 2019 Aug 1;288:65-67.
  • Arghami A, Krajewski A, Leduc C, Lin P, Gloviczki P. Open Staged Repair of Splenic and Extensive Superior Mesenteric Artery Aneurysms. Journal of Vascular Surgery. 2019 Apr;69(4):1252-1256.

  • Leduc C, Buonocore D, Rekhtman N, et al. Section 4 (Chapters 33-46): Benign neoplasms in Pulmonary pathology: An atlas and Text. 3rd edition. Wolters Kluwer Health. 2018.

  • Baudhuin L, Leduc C, Train L, Avula R, Kluge M, Kotzer K, Lin P, Ackerman M, Maleszewski J. Technical Advances for the Clinical Genomic Evaluation of Sudden Cardiac Death: Verification of Next-Generation Sequencing Panels for Hereditary Cardiovascular Conditions Using Formalin-Fixed Paraffin-Embedded Tissues and Dried Blood Spots. Circulation : Cardiovascular Genetics. 2017 Dec;10(6): e001844.
  • Nagaria T, Shi C, Leduc C, Hoskin V, Sikdar S, Sangrar W, Greer P. Combined targeting of Raf and Mek synergistically inhibited tumorigenesis in a triple negative breast cancer model. Oncotarget. 2017 Oct 6; 8(46) : 80804-80819.

  • Leduc C, Sukov W, Rustin J, Maleszewski J. Cardiac Angiosarcoma: Histopathologic, Immunohistochemical, and Molecular Genetic Analysis of 10 Cases. Human Pathology. 2017 Feb; 60:199-207.

  • Naidoo J, Wang X, Woo K, Iyriboz T, Halpenny D, Cunningham J, Chaft J, Segal N, Callahan M, Lesokhin A, Rosenberg J, Voss M, Rudin C, Rizvi H, Hou X, Rodriquez K, Albano M, Gordon R, Leduc C, Rekhtman N, Harris B, Menzies A, Guminski A, Carlino M, King B, Wolchok J, Postow M, Long G, Hellmann M. Pneumonitis in Patients Treated With Anti-Programmed Death-1/Programmed Death Ligand 1 Therapy. Journal of Clinical Oncology. 2017 Mar;35(7):709-717
  • Leduc C, Maleszewski J. Letter to the editor: Misconceptions about Malignant Metamorphosis in Myxoma. The Annals of Thoracic Surgery. 2016 Nov; 102(5):1766.

  • Helder M, Kouhoukos N, Zehr K, Dearani J, Maleszewski J, Leduc C, Heins C, Schaff H. Late Durability of Decellularized Allografts for Aortic Valve Replacement: a Word of Caution. Journal of Thoracic and Cardiovascular Surgery: 2016 Oct;152(4):1197-9
  • Leduc C, Zhang L, Öz B, Luo J, Fukuoka J, Antonescu C, Travis W. Thoracic myoepithelial tumors: a pathologic and molecular study of 8 cases with review of the literature. American Journal of Surgical Pathology, 2016; 40(2):212-23.

  • Leduc C, Pacheco-Blandino I, Squire J, Farmer P, Good D, Lebrun D. Composite mantle cell and primary cutaneous anaplastic large cell lymphoma: case report and review of the literature. American Journal of Dermatopathology, 2015 Mar; 37(3):232-6.
  • Leduc C, Young I, Joneja M, Parker C. Unexpected post-mortem diagnosis of systemic sclerosis presenting as pneumatosis intestinalis: revised diagnostic criteria and medicolegal implications. Legal Medicine, 2015 Jan; 17(1):29-33.
  • Cases M, Leduc C, Farmer P, Richardson S, Zoutman R. HSV lymphadenitis: The elusive doppelganger in the immunocompromised patient. Internal Medicine, 2014; 53(21):2539-42.

  • Nagaria T, Williams J, Squire J, Leduc C, Greer P, Sangrar W. Flavopiridol synergizes with Sorafenib to induce cytotoxicity and potentiate anti-tumorigenic activity in EGFR/HER-2 and mutant RAS/RAF breast cancer model systems. Neoplasia, 2013; 15 (8): 939-951.

  • Yanagawa N, Leduc C, Kohler D, Saieg M, John T, Sykes J, Yoshimoto M, Pintillie M, Squire J, Shepherd F, Tsao M-S. Loss of phosphatase and tensin homolog (PTEN) protein expression is an independent prognostic marker in lung adenocarcinoma. Journal of Thoracic Oncology, 2012; 7 (10): 1513-1521.